A new study, published in the scientific journal “Cell”, shows that SARS-CoV-2 ( that is COVID-19) binds to human cells similarly to the original coronavirus - SARS (SARS-CoV) that caused a worldwide outbreak in 2003. In both cases viral proteins - the so-called protein "spikes" - are responsible for the connection of the virus with human cells.
Along with this process, the spike protein must be primed with an enzyme called protease so that the virus can completely penetrate the cell. Research has shown that, like SARS-CoV, SARS-CoV-2 (COVID-19) uses the TMPRSS2 protease to complete the cell's infection process.
Scientists focused on finding any compound that could prevent the TMPRSS2 protease from working and stop the entry of coronavirus into the cell.
In previous SARS-CoV studies, cysteines - proteins with anti-inflammatory and osteogenic properties - have already been investigated.
Research results showed that cysteines inhibit protease production, including these of the coronovirus group. To date, the possibility of cysteine suppression of the protease in COVID-19 is being investigated.
There exists phytocystatins. These are plant cystatins, usually present in large quantities in plant tissues and controlling the accumulation and degradation of storage proteins. One of these plants is sea buckthorn.
Scientists from the Molecular Physiology and Proteomics Laboratory, Department of Botany, University of Delhi, New Delhi, India, studying a set of sea buckthorn proteins, found, among other things, phytocystatins, which suggests that sea buckthorn may possibly partially suppress the development of COVID-19 disease.
Sea buckthorn is already being studied for the possibility of suppressing COVID-19, since it contains lactobacilli that suppress purines necessary for the development of coronavirus, as well as succinic and malic acid, which are antiviral agents.
Thus, in the absence of any medicine against coronavirus, sea buckthorn can serve as an excellent supplementary remedy for the prevention and control of COVID-19.#covıd_19 #covid #coronavid19 #coronavirus #antiviral #antiviralherbs #seabuckthorn #seabuckthornoil #cedarnutoil #ringingcedars